แอโรซิน-บี

• POLYMYXIN B SULFATE*ต่อ 1 vial

ประเภทควบคุม

ยาควบคุมพิเศษ

ข้อบ่งใช้

- ยานี้ใช้เพื่อรักษาการติดเชื้อแบคทีเรียแกรมลบที่ไม่สามารถใช้ยาปฏิชีวนะตัวอื่นได้ โดยแพทย์พิจารณาแล้วว่าเหมาะสมที่จะใช้ยานี้ - Polymyxin B for injection (polymyxin B sulphate) is used as monotherapy or combination with relevant antibiotics for the treatment of extensively drug-resistant gram negative bacterial infections with limited treatment options, mainly the susceptible strains of Acinetobacter baumannii, Pseudomonas aeruginosa and Klebsiella pneumonia. - Polymyxin B for Injection is indicated for the treatment of patients with the following infections, when caused by susceptible strains of the designated aerobic gram negative bacteria. - Urinary tract infections caused by Pseudomonas aeruginosa and Escherichia coli. - Bloodstream infections caused by Pseudomonas aeruginosa, Enterobacter (formerly called Aerobacter) aerogenes and Klebsiella pneumonia. - Meningeal infections caused by Pseudomonas aeruginosa. NOTE: IN MENINGEAL INFECTIONS, POLYMYXIN B SULFATE SHOULD BE ADMINISTERED ONLY BY THE INTRATHECAL ROUTE. - Polymyxin B for injection should be used where sensitivity suggests more commonly used systemic antibacterial agents may be contraindicated or ineffective because of bacterial resistance. - Polymyxin B for injection, if prescribed for intravenous, intramuscular or intrathecal administration, should be used only in hospitalized patients under close monitoring for kidney function and neurological signs and symptoms. - To reduce the development of drug-resistant bacteria and maintain the effectiveness of polymyxin B sulphate and other antibacterial drugs, polymyxin B for injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

รหัส ATC

J01XB02 (polymyxin B)

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